A few of the most useful operations are located under the File menu, selected from the task bar:
Capture Events – This menu item turns capture on and off so that you can control when to start capturing activity.
Save… – Once you’ve captured the activity you need, a log of that activity can be saved to a ProcMon log file (.PML). This log can later be opened by ProcMon on any other system.
Open… -- Used to open a PML file containing a previously captured log.
Another particularly useful operation, under the Edit menu:
Clear Display – This menu item clears the display so that any logs you capture will be “clean”.